Peptide Database

Peptide NameTenecteplase

Function Ontology

Hemostasis ▸ Fibrinolytic activity

Standard StatusStandard

Sequence Length255 amino acids

Chemical FormulaC1238H1864N366O381S23

DescriptionStandard

        SYQVICRDEKTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGNWSTAESGAECTQWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEY
    

Molecular Weight28707.76 Da

Isoelectric Point (pI)8.42

Net Charge (pH 7.0)5.79

Net Charge (pH 7.4) 4.91

Charge Density (pH 7.0) 0.0227

GRAVY Index-0.69

Hydrophobic Moment 0.74

Boman Index-0.11

Instability Index37.72

Aliphatic Index 47.49

Aromaticity 0.1176

Extinction Coeff. Reduced 66350.00

Extinction Coeff. Oxidized 67600.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0217943 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyFibrinolytic protein

Tax ID9606

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Thrombolytic Fibrinolytic

Half-Life1.9 h (mammalian reticulocytes, in vitro)