Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length401 amino acids

Chemical FormulaC2034H3146N530O591S13

DescriptionStandard

        MHDLSGSYGIGWLGSVNYVFSGMRIHRFLLQDSQLSLHPGQGIKASLSDNYISVGGNWKVEKSFITLHGTFDLSVDGISILVSLNLGKDQSGRPTVSVIHCHNSISHVSVEISGHISWILNLFHERIENNVKPILEQKICEMVRKSAISRLEPYLRTLPVTLMIDQIAGIDYSLVGAPQVTSQGLDTHFKGEFFSRNWNTSVPFDAPPITLPQKHDHMIYFAVSEYAFNTASRVYYQAGQMKFTIQNKHLAMLYPNMELELETSPESAPFLTFTPGNVTFMPVMDIQAFVLLPNSAGRKSLFQIRASTNISITINVNSTRITGSLTTGSELKLELKDSNIGFFNVNLMESIFNYYALHTVYPSLNAKLEEGIPLPLPRDTYLNSLEFQIHENFLFLGANVD
    

Molecular Weight44896.78 Da

Isoelectric Point (pI)6.09

Net Charge (pH 7.0)-6.16

Net Charge (pH 7.4) -7.26

Charge Density (pH 7.0) -0.0154

GRAVY Index-0.02

Hydrophobic Moment 0.67

Boman Index0.13

Instability Index35.79

Aliphatic Index 96.23

Aromaticity 0.1022

Extinction Coeff. Reduced 42860.00

Extinction Coeff. Oxidized 42985.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0295575 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria