Peptide Database

Peptide NameMotilin(1–12)ghrelin(12–16)

Function Ontology

Gastrointestinal bioactivity ▸ Gastrointestinal motility

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC98H153N27O25

DescriptionStandard

        FVPIFTYGELQRVQQRK
    

Molecular Weight2109.43 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.1036

GRAVY Index-0.51

Hydrophobic Moment 0.48

Boman Index-0.12

Instability Index41.82

Aliphatic Index 80.00

Aromaticity 0.1765

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 876.98

LogP -6.17

H-bond Donors 30.0

H-bond Acceptors 27.0

Rotatable Bonds 69.0

Heavy Atoms 150.0

Ring Count 4.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0312809 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyMotilin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Gastrointestinal motility

TargetGPR38 agonist activity

Activity0.01-0.01 μM

MethodEC50

Half-LifeIntravenouly injected in Sprague-Dawley rats, in vivo; 144 s