Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC363H592N118O102S13

DescriptionStandard

        MKLSMRLISAVLIMFMIFVATGMGPVTVEARTCESQSHRFKGTCVSDTNCANVCHNERFGGGRCRGFRRRCFCTRNC
    

Molecular Weight8658.16 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)7.60

Net Charge (pH 7.4) 7.16

Charge Density (pH 7.0) 0.0987

GRAVY Index0.00

Hydrophobic Moment 0.55

Boman Index-0.06

Instability Index39.13

Aliphatic Index 58.18

Aromaticity 0.0779

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3581.71

LogP -42.97

H-bond Donors 139.0

H-bond Acceptors 125.0

Rotatable Bonds 290.0

Heavy Atoms 596.0

Ring Count 9.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0133072 VERIFIED: NO

Provenance & Taxonomy

OrganismArabis alpina [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence