Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC191H314N76O53S

DescriptionStandard

        YGRKKRRQRRRGGGLGASWHRPDKGGGGLRRMADDLNAQY
    

Molecular Weight4555.08 Da

Isoelectric Point (pI)11.72

Net Charge (pH 7.0)8.85

Net Charge (pH 7.4) 8.58

Charge Density (pH 7.0) 0.2211

GRAVY Index-1.68

Hydrophobic Moment 0.62

Boman Index-0.54

Instability Index97.55

Aliphatic Index 36.75

Aromaticity 0.0750

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2170.92

LogP -27.39

H-bond Donors 81.0

H-bond Acceptors 64.0

Rotatable Bonds 158.0

Heavy Atoms 321.0

Ring Count 6.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0296676 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Apoptosis induction Antitumor Anticancer Cytotoxic

TargetHCT116 human colon cancer cells; HCT116 xenograft

Activity56.9 %

Methodin vivo tumor growth inhibition