Peptide Database

Peptide NameCycloviolacin O25

Function Ontology

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Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC124H188N30O38S6

DescriptionStandard

        CGESCVYIPCFTGIAGCSCKSKVCYYN
    

Molecular Weight2899.39 Da

Isoelectric Point (pI)7.76

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.40

Charge Density (pH 7.0) 0.0259

GRAVY Index0.46

Hydrophobic Moment 0.26

Boman Index0.21

Instability Index23.81

Aliphatic Index 54.07

Aromaticity 0.1481

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1085.17

LogP -12.15

H-bond Donors 44.0

H-bond Acceptors 45.0

Rotatable Bonds 89.0

Heavy Atoms 198.0

Ring Count 5.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0427095 VERIFIED: YES

Provenance & Taxonomy

OrganismPigea floribunda [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)