Peptide Database

Peptide NameMegicin-18

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC104H161N23O21

DescriptionStandard

        FFGALFKLATKIIPSLFR
    

Molecular Weight2069.53 Da

Isoelectric Point (pI)11.17

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1532

GRAVY Index1.08

Hydrophobic Moment 0.67

Boman Index0.38

Instability Index-3.96

Aliphatic Index 119.44

Aromaticity 0.2222

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 703.63

LogP -1.09

H-bond Donors 25.0

H-bond Acceptors 24.0

Rotatable Bonds 66.0

Heavy Atoms 148.0

Ring Count 5.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0411270 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus gibbosus [Animal]

FamilyMeucin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

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