Peptide Database

Peptide NameSyn-safencin-7

Function Ontology

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC130H229N41O33

DescriptionStandard

        AGKETIRQKLKNEIKKKGRKAVIAW
    

Molecular Weight2894.46 Da

Isoelectric Point (pI)10.73

Net Charge (pH 7.0)6.79

Net Charge (pH 7.4) 6.59

Charge Density (pH 7.0) 0.2718

GRAVY Index-1.03

Hydrophobic Moment 0.65

Boman Index-0.35

Instability Index8.03

Aliphatic Index 86.00

Aromaticity 0.0400

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1264.46

LogP -10.40

H-bond Donors 45.0

H-bond Acceptors 40.0

Rotatable Bonds 108.0

Heavy Atoms 204.0

Ring Count 2.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0090319 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic

TargetL. donovani

Activity0.77 μM

MethodIC50

RECORD: Rec_0317584 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic Toxicity

TargetTHP-1 cells

Activity>20 μM

MethodCC50