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MYP_105257
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
14 amino acids
C64H108N22O18S
Standard
Sequence
YKQCHKKGGKKGSG
Physicochemical Analysis
1505.74 Da
10.03
4.83
4.55
0.3451
-1.96
0.47
-0.46
51.61
0.00
0.0714
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
683.95
-9.03
25.0
25.0
56.0
105.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0155483 VERIFIED: YES
Provenance & Taxonomy
Crotalus durissus terrificus [Animal]
Crotamine/CyLoP-1
8732
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorophore labeling
None
N-term detail: Labelled with rhodamine B dye
Bio-Activity Profile
Cell-penetrating peptide
HeLa
Fluorescence-based uptake assay
PMID18983137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18983137/
RECORD: Rec_0188864 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HeLa (Not active up to 100 μM)
PaperPubMed PMID: 18983137 PMID18983137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18983137/
RECORD: Rec_0236975 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human cervical carcinoma HeLa
PMID28314993;18983137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28314993/
RECORD: Rec_0241553 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium tuberculosis H37Rv
300 μM
MIC
PMID28314993;18983137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28314993/
RECORD: Rec_0247954 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
NrTP1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine conjugation
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID25620660 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25620660/
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