Peptide Database

Peptide NameGramicidin A [l14k]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC96H136N20O16

DescriptionStandard

        VGALAVVVWLWLWKW
    

Molecular Weight1826.23 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)0.73

Net Charge (pH 7.4) 0.52

Charge Density (pH 7.0) 0.0489

GRAVY Index1.59

Hydrophobic Moment 0.19

Boman Index0.73

Instability Index46.04

Aliphatic Index 168.67

Aromaticity 0.2667

Extinction Coeff. Reduced 22000.00

Extinction Coeff. Oxidized 22000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 559.90

LogP 4.64

H-bond Donors 21.0

H-bond Acceptors 17.0

Rotatable Bonds 51.0

Heavy Atoms 132.0

Ring Count 8.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084705 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStreptococcus pyogenes ATCC 19615

Activity0.16 μM

MethodMIC

RECORD: Rec_0151882 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus ATCC 6538

Activity2.5 μM

MethodMIC

RECORD: Rec_0247235 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Bio-Activity Profile

Function

Hemolytic

TargetHuman erythrocytes (50% Hemolysis at 05-Oct microM

MethodHemolysis

RECORD: Rec_0370342 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetBacillus subtilis ATCC 6633

Activity5 μM

MethodMIC

RECORD: Rec_0398142 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli BL21