Peptide Database

Peptide NameEnterocin AS-48 (46-70)[R3S,S5R,K7W,A8K,Y9E,E13Y,K17G,G18K,R20V,A21I,V22R,I23A]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC140H232N40O32

DescriptionStandard

        AGSERIWKELKKYIKKGKKVIRAAW
    

Molecular Weight2987.59 Da

Isoelectric Point (pI)10.46

Net Charge (pH 7.0)6.79

Net Charge (pH 7.4) 6.59

Charge Density (pH 7.0) 0.2717

GRAVY Index-0.84

Hydrophobic Moment 0.91

Boman Index-0.25

Instability Index0.32

Aliphatic Index 86.00

Aromaticity 0.1200

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1214.30

LogP -6.26

H-bond Donors 45.0

H-bond Acceptors 39.0

Rotatable Bonds 107.0

Heavy Atoms 212.0

Ring Count 5.0

Amide Bonds 24.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0309084 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetSheep erythrocytes (10.5% Hemolysis at >32 μM

Activity32 μM

MethodHemolysis

RECORD: Rec_0384189 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli BL21

Activity2 μM

MethodMIC