Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC327H515N79O83S8

DescriptionStandard

        MSCYRVVVLALLVVLLLNVVENEAASFPWSCPSLSGVCRKVCLPTELFFGPLGCGKGFLCCVSHFL
    

Molecular Weight7137.59 Da

Isoelectric Point (pI)7.55

Net Charge (pH 7.0)0.52

Net Charge (pH 7.4) 0.15

Charge Density (pH 7.0) 0.0079

GRAVY Index1.10

Hydrophobic Moment 0.48

Boman Index0.37

Instability Index34.32

Aliphatic Index 119.39

Aromaticity 0.1061

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2499.89

LogP -16.16

H-bond Donors 93.0

H-bond Acceptors 93.0

Rotatable Bonds 223.0

Heavy Atoms 497.0

Ring Count 13.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0268608 VERIFIED: NO

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

RECORD: Rec_0404792 VERIFIED: NO

Provenance & Taxonomy

OrganismLates calcarifer [Bacterium]

FamilyDefensin

Tax ID8187

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence