Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC336H576N108O89S9

DescriptionStandard

        MKRVKLMSSQGKKTKLFLSPLETQKALLFKRNEDLICYCRTRGCKRRERLNGTCRKGHLMYTLCCR
    

Molecular Weight7841.42 Da

Isoelectric Point (pI)10.27

Net Charge (pH 7.0)13.53

Net Charge (pH 7.4) 13.15

Charge Density (pH 7.0) 0.2049

GRAVY Index-0.66

Hydrophobic Moment 0.47

Boman Index-0.33

Instability Index45.73

Aliphatic Index 70.91

Aromaticity 0.0606

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3289.85

LogP -32.93

H-bond Donors 127.0

H-bond Acceptors 113.0

Rotatable Bonds 279.0

Heavy Atoms 542.0

Ring Count 6.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0011689 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence