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MYP_105123
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Basic Information
Antimicrobial peptide Lasioglossin LL-II
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
15 amino acids
C84H148N22O17
Standard
Sequence
VNWKKILGKIIKVAK
Physicochemical Analysis
1738.21 Da
10.60
4.73
4.51
0.3153
0.21
0.71
0.07
-13.04
149.33
0.0667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
659.70
-1.42
23.0
22.0
63.0
123.0
2.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029504 VERIFIED: NO
Provenance & Taxonomy
Lasioglossum laticeps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Antitumor Toxin Hormone
RECORD: Rec_0030262 VERIFIED: YES
Provenance & Taxonomy
Lasioglossum laticeps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytotoxic Hemolytic
Pseudomonas aeruginosa (Gram-negative)
PMID19591185;23159628 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19591185/
RECORD: Rec_0033588 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
1.4 μM
MIC
PMID19591185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19591185/
RECORD: Rec_0058353 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 53.3%, E 0.0%, T 13.3%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0104137 VERIFIED: YES
Provenance & Taxonomy
Lasioglossum laticeps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Escherichia coli
1.4 μM
MIC
PaperLasioglossins: Three Novel Antimicrobial Peptides from the Venom of the Eusocial Bee Lasioglossum laticeps (Hymenoptera: Halictidae).
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