Peptide Database

Peptide NameDEFB118

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length102 amino acids

Chemical FormulaC472H759N145O162S7

DescriptionStandard

        SGEKKCWNRSGHCRKQCKDGEAVKDTCKNLRACCIPSNEDHRRVPATSPTPLSDSTPGIIDDILTVRFTTDYFEVSSKKDMVEESEAGRGTETSLPNVHHSS
    

Molecular Weight11281.41 Da

Isoelectric Point (pI)6.39

Net Charge (pH 7.0)-1.23

Net Charge (pH 7.4) -1.76

Charge Density (pH 7.0) -0.0120

GRAVY Index-0.89

Hydrophobic Moment 0.64

Boman Index-0.22

Instability Index55.28

Aliphatic Index 51.57

Aromaticity 0.0392

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4978.96

LogP -66.38

H-bond Donors 180.0

H-bond Acceptors 172.0

Rotatable Bonds 376.0

Heavy Atoms 786.0

Ring Count 15.0

Amide Bonds 106.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0093954 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0286557 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

TargetEscherichia coli. Antimicrobial robustness: The activity is structure deppendent