Peptide Database

Peptide NameC-type natriuretic peptide 2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC110H189N37O34S4

DescriptionStandard

        GRSSMVGGRGCFGMKIDRIGSISGLGC
    

Molecular Weight2702.16 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.51

Charge Density (pH 7.0) 0.1015

GRAVY Index0.21

Hydrophobic Moment 0.52

Boman Index0.09

Instability Index25.38

Aliphatic Index 68.52

Aromaticity 0.0370

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1149.86

LogP -16.13

H-bond Donors 45.0

H-bond Acceptors 41.0

Rotatable Bonds 94.0

Heavy Atoms 185.0

Ring Count 1.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0022615 VERIFIED: YES

Provenance & Taxonomy

OrganismTakifugu rubripes [Animal]

FamilyC-type natriuretic peptide

Tax ID31033

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide11-27

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0117321 VERIFIED: NO

Provenance & Taxonomy

OrganismFugu rubripes,Takifugu rubripes [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide11-27

Bio-Activity Profile

Function

Neuropeptide