Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2304H3658N626O646S10

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGVAILEKELAQLKLPDISGDSRVLRVGKVRYELSRLRLRDFHLPYSRITPISNVGLQVSISNAFAELDGDWRVKFLFVRDHGSFDIKVENVYIKISLRLGSDSTGKPTVSTSDCSARISKVRVLFSGKFGWLYNLFHSSIESRFRKILEDKVCANVVKSVQNDLQRYIQTLPVTARIDDKTGIDYSLVTSPRASPQSLDADLKGEFYSLAHRSTVPFSPLPLAFPSDHDRMVYFGASSYFFNTASIAYHKAGALVFEITEAMIPKDAGFSLNTSIFSAFIPQLEEMYPNMPMKFRLSAPTAPFLTIGPGGILLKPIVDAQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGRIVGSLDVGRIRLSLKDSAVGTFQVRMMQSLMNILTSSTLLPRLNARLDEGFPLPLLDRIRLSNILVRFHQNFLLLGADVHFQPR
    

Molecular Weight50784.15 Da

Isoelectric Point (pI)9.67

Net Charge (pH 7.0)13.20

Net Charge (pH 7.4) 12.43

Charge Density (pH 7.0) 0.0289

GRAVY Index0.07

Hydrophobic Moment 0.68

Boman Index0.08

Instability Index34.16

Aliphatic Index 103.46

Aromaticity 0.0943

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30495.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0112182 VERIFIED: NO

Provenance & Taxonomy

OrganismPicathartes gymnocephalus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria