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MYP_105008
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Basic Information
Maculatin 1.3
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
21 amino acids
C98H159N25O24
Standard
Sequence
GLLGLLGSVVSHVVPAIVGHF
Physicochemical Analysis
2071.46 Da
6.92
-0.07
-0.37
-0.0031
1.62
0.40
0.65
14.84
166.67
0.0476
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
734.35
-4.18
25.0
26.0
63.0
147.0
4.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014368 VERIFIED: YES
Provenance & Taxonomy
Litoria eucnemis [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C-terminal NH2
Bio-Activity Profile
Antimicrobial Antiviral Anticancer
Human immunodeficiency virus 1 (HIV-1)
4.0 μM
EC50
PaperHost-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance.
RECORD: Rec_0017857 VERIFIED: YES
Provenance & Taxonomy
Litoria eucnemis [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
C-terminal NH2
Bio-Activity Profile
Antimicrobial Antiviral Anticancer
Bacillus subtilis
25 μM
MIC
PaperHost-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance.
RECORD: Rec_0130524 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0142284 VERIFIED: NO
Provenance & Taxonomy
Fringed tree [Animal]
Maculatin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0157586 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Antiviral Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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