Peptide Database

Peptide NameDefA

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC202H305N61O64S6

DescriptionStandard

        DKLIGSCVWGAVNYTSDCNAECKRRGYKGGHCGSFANVNCWCET
    

Molecular Weight4804.34 Da

Isoelectric Point (pI)7.77

Net Charge (pH 7.0)0.79

Net Charge (pH 7.4) 0.44

Charge Density (pH 7.0) 0.0180

GRAVY Index-0.42

Hydrophobic Moment 0.55

Boman Index-0.03

Instability Index37.55

Aliphatic Index 44.32

Aromaticity 0.1136

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2039.91

LogP -25.88

H-bond Donors 78.0

H-bond Acceptors 72.0

Rotatable Bonds 155.0

Heavy Atoms 333.0

Ring Count 8.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0290501 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC 6538P

Activity1

MethodMIC

RECORD: Rec_0392493 VERIFIED: YES