Peptide Database

Peptide NameTemporin-1Va

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC65H111N15O17

DescriptionStandard

        FLSSIGKILGNLL
    

Molecular Weight1374.67 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0584

GRAVY Index1.32

Hydrophobic Moment 0.57

Boman Index0.50

Instability Index19.27

Aliphatic Index 180.00

Aromaticity 0.0769

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 522.09

LogP -3.01

H-bond Donors 18.0

H-bond Acceptors 18.0

Rotatable Bonds 47.0

Heavy Atoms 97.0

Ring Count 1.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0150588 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 53.8%, E 0.0%, T 23.1%, C 23.1% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antibacterial Toxic Antimicrobial Antifungal Hemolytic Anti-Gram-positive Anti-Gram-negative

RECORD: Rec_0151599 VERIFIED: YES

Provenance & Taxonomy

OrganismRana catesbeiana [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

RECORD: Rec_0154211 VERIFIED: YES

Provenance & Taxonomy

OrganismRana virgatipes [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic

Targetwashed human erythrocytes

Activity120 μM

MethodLD50

RECORD: Rec_0180051 VERIFIED: YES

Provenance & Taxonomy

OrganismRana virgatipes [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetEnterobacter cloacae HNTCC 53001

Activity40 μM

MethodMIC

RECORD: Rec_0183252 VERIFIED: YES

Provenance & Taxonomy

OrganismRana virgatipes [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetEnterococcus faecalis ATCC 29212

Activity40 μM

MethodMIC

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