Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC589H952N168O186S9

DescriptionStandard

        MKLLLLALPMLVFLPQGILAYSGEKKCWNRSGHCRKQCKDGEAVKDTCKNLRACCVPSNEDHRRVPTTSPTPLSDSTPGIIDDILTVRFTTDYFEVSSKKDMIEESEAGRGTETSLPNVHHSS
    

Molecular Weight13651.46 Da

Isoelectric Point (pI)6.88

Net Charge (pH 7.0)-0.19

Net Charge (pH 7.4) -0.73

Charge Density (pH 7.0) -0.0015

GRAVY Index-0.46

Hydrophobic Moment 0.64

Boman Index-0.08

Instability Index55.01

Aliphatic Index 74.47

Aromaticity 0.0488

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5682.05

LogP -63.99

H-bond Donors 203.0

H-bond Acceptors 199.0

Rotatable Bonds 453.0

Heavy Atoms 952.0

Ring Count 19.0

Amide Bonds 128.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0252211 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyDefensin

Tax ID9593

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence