Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length626 amino acids

Chemical FormulaC2971H4878N872O948S9

DescriptionStandard

        MGKNNSGGYGGSNLGGHTTDHGNGKSTTSDNRGDISHHTDSGSSKGDHGLGRGSGGSGGSSSSRGDAPENASRVNMAHAGIPVALYPVSGVLTVSLNWPTITAAVREAFIGLDTYLGNSLARTAPYAGRLLGVVVGSLLPGQIAPDPKFSYNLKDPQVDKDNPYSVTALPAELVTSVPVADIPKNTTVPARVLAQAVIDELTQTRPVTITPVKSTPVPVVKAQKTNKHNVYTAQVVPGMKPVRIHVSSYPDKFQVMPNSTPAVKQYLSHPDEGRSHHAILDFGRDHAPVYVSVTKQLKPEEEKKLAEKARKEWVADNSAGVIKVLADINTLIISTEKQMSAKQQELRNKQAELQDLSKELMVKNARDKKKREINTVINQLTADLSNIQKELANAEGNKTLNEKTLAELKEQELNQVNTPEDAEKELAAANIALTKARTRVAEKEKPLAAKRQELKNKQAELQDLSKELMVKNARDKKKREINIVINQLSTEVGLLEKALSDAMESRNKAEGKKKVAEDKVKEAKDKKGKTPELKLDEKIKEQMSGRGWTEQDVKDTVAKGPKGKSFDKRSPKKTPPDHLGRNDTATVYGKPGEYVVVNDRTGEVVQVSDKTDPKWVDDSRIQWERK
    

Molecular Weight68270.37 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)16.72

Net Charge (pH 7.4) 15.62

Charge Density (pH 7.0) 0.0267

GRAVY Index-0.73

Hydrophobic Moment 0.71

Boman Index-0.14

Instability Index31.96

Aliphatic Index 77.72

Aromaticity 0.0351

Extinction Coeff. Reduced 45380.00

Extinction Coeff. Oxidized 45380.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371196 VERIFIED: NO

Provenance & Taxonomy

OrganismMorganella sp. [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence