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MYP_104949
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Basic Information
FALL-39
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
39 amino acids
C217H354N62O55
Standard
Sequence
FALLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
Physicochemical Analysis
4711.51 Da
10.61
5.76
5.55
0.1478
-0.57
0.97
-0.24
22.66
87.44
0.1282
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1959.32
-14.40
70.0
61.0
167.0
334.0
6.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0102153 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
L.rhamnosus 81
>100 μM
MIC
PaperFALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis.
RECORD: Rec_0104143 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Cathelicidin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Listeria monocytogenes
PMID7529412 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7529412/
RECORD: Rec_0114448 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Enterococcus faecalis
>100 μM
MIC
PaperFALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis.
RECORD: Rec_0125101 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
microorganisms Escherichia coli
25 μM
MIC
PaperFALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis.
RECORD: Rec_0137869 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Lactobacilli strains are resistant to this peptide L.rhamnosus GR-1
>100 μM
MIC
PaperFALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis.
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