Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length201 amino acids

Chemical FormulaC996H1593N277O270S9

DescriptionStandard

        PMTPPVAHEPMLLLAVTEFVANSAASTYFTAGALRRNISSDMLPQRFPLQLRTKSMEVFSPQLQERYPDRPMELHLWARRQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGVTVRLTGLVPDPELGAGPVHPSTLPALCRAQGLPVPQVKRLETLLKFGLWLFGVPRVNSKCCPSPVP
    

Molecular Weight22056.58 Da

Isoelectric Point (pI)9.76

Net Charge (pH 7.0)7.38

Net Charge (pH 7.4) 6.98

Charge Density (pH 7.0) 0.0367

GRAVY Index0.03

Hydrophobic Moment 0.54

Boman Index0.08

Instability Index59.19

Aliphatic Index 95.07

Aromaticity 0.0647

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0014320 VERIFIED: NO

Provenance & Taxonomy

OrganismRegulus satrapa [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria