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MYP_104899
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Basic Information
Antifungal protein Pr-2
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Plant bioactivity ▸ Plant defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
15 amino acids
C62H109N25O22
Standard
Sequence
QGIGVGDNDGKRGKR
Physicochemical Analysis
1556.68 Da
9.99
1.76
1.55
0.1174
-1.61
0.57
-0.44
24.50
45.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
807.34
-12.08
28.0
24.0
57.0
109.0
0.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0039896 VERIFIED: NO
Provenance & Taxonomy
Cucurbita maxima [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Fungicide Plant Defense Anti-Candida Antiparasitic Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic Non-ribosomal
Aspergillus fumigatus, A.parasiticus, Botrytis cinerea, Candida albicans, C.coccodes, Escherichia coli, Fusarium oxysporum, F.solani, P.verrucosum, T.harzianum, T.viride
Qualitative functional evidence
PMID19807165 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19807165/; https://www.uniprot.org/uniprotkb/P86796/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0060843 VERIFIED: YES
Provenance & Taxonomy
Cucurbita maxima [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Colletotrichum coccodes
PMID19807165 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19807165/
RECORD: Rec_0071015 VERIFIED: YES
Provenance & Taxonomy
Cucurbita maxima [Plant]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
20 μM
EC50
PMID19807165 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19807165/
RECORD: Rec_0084359 VERIFIED: YES
Provenance & Taxonomy
Cucurbita maxima [Plant]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Low hemolytic activity against human erythrocyte
Hemolysis
PMID19807165 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19807165/
RECORD: Rec_0088880 VERIFIED: YES
Provenance & Taxonomy
Cucurbita maxima [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Trichoderma viride
PMID19807165 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19807165/
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