Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2323H3641N579O669S15

DescriptionStandard

        MKVKAIYPGIKARATQRALDYAVQAGMEMIEQMAKERKLPDLKGSESLEFLKIDYVNYNFTNIKINAFSFPNTSLAFVPGVGIRALTNHGTTNISTDWEVKSALFQDTGAADLFLSGVYFTGIVVLSRNDFGHPILKLQDCYAQVSHADVSFSGELSVLYNSFAEPMEKPILKKLNEMLCPIITGEVEALNANLSMLEVLRKIDNYTLLDYSLVSSPEITENYFDLNLKGVFYPLKTLQYPPFPSVPFVLPERSDSMLYVGISKYFFKSASYAYFTAGAFSFTLTTKEISNHLLHNSQALGNMLTRIAELYILSQPFMVQVTATEPPVISLLPGNFTLDIPASIMILTQPKNSTAETIVSMDFVASTNVALAILGQRLICSLSLNRFRLSLPESNRSNIEVLRFENILSSILHFGVLPLANAKLQQGFPLPNPHKISLVNSDIEVLEPKEFYKRDI
    

Molecular Weight50865.21 Da

Isoelectric Point (pI)5.88

Net Charge (pH 7.0)-4.87

Net Charge (pH 7.4) -5.60

Charge Density (pH 7.0) -0.0107

GRAVY Index0.11

Hydrophobic Moment 0.68

Boman Index0.14

Instability Index37.80

Aliphatic Index 102.43

Aromaticity 0.1031

Extinction Coeff. Reduced 32320.00

Extinction Coeff. Oxidized 32445.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0228287 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria