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MYP_104855
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Basic Information
D Magainin-2 [S8A,G13A,G18A]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
23 amino acids
C116H184N30O28S
Standard
Sequence
GIGKFLHAAKKFAKAFVAEIMNS
Physicochemical Analysis
2478.95 Da
10.00
2.85
2.59
0.1237
0.39
0.70
0.22
10.56
85.22
0.1304
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
936.90
-6.08
32.0
33.0
85.0
175.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0063168 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Fusobacterium nucleatum ATCC 25586
0.4
MBC
PMID3410055;26986223;14642822;24102563;26369301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3410055/
RECORD: Rec_0070205 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
2.5 μg/mL
MIC
PMID3410055;26986223;14642822;24102563;26369301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3410055/
RECORD: Rec_0093563 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Rabbit erythrocytes
200 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/9442044/ PMID9442044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9442044/
RECORD: Rec_0097441 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
H-1299
60 μg/mL
LD50
PaperShort bioactive peptides Evidence URLhttps://patents.google.com/patent/US6875744B2/en PatentUS6875744B2
RECORD: Rec_0100388 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
C. parasitica
10 μM
MIC
PaperSynthetic antimicrobial peptide design
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