Peptide Database

Peptide NameSLAY-screened peptide P2063

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC48H87N21O16

DescriptionStandard

        RAVNDISRRQ
    

Molecular Weight1214.34 Da

Isoelectric Point (pI)11.70

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.56

Charge Density (pH 7.0) 0.1761

GRAVY Index-1.43

Hydrophobic Moment 0.77

Boman Index-0.72

Instability Index104.80

Aliphatic Index 78.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 654.63

LogP -9.12

H-bond Donors 24.0

H-bond Acceptors 18.0

Rotatable Bonds 42.0

Heavy Atoms 85.0

Ring Count 0.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390636 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/