Peptide Database

Peptide NameConotoxin Cl14.8

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC105H171N29O34S6

DescriptionStandard

        DCGRCPLGQYCDAEAGMCKPTLIM
    

Molecular Weight2576.04 Da

Isoelectric Point (pI)4.56

Net Charge (pH 7.0)-1.28

Net Charge (pH 7.4) -1.54

Charge Density (pH 7.0) -0.0532

GRAVY Index0.03

Hydrophobic Moment 0.29

Boman Index0.07

Instability Index19.35

Aliphatic Index 57.08

Aromaticity 0.0417

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 998.41

LogP -10.34

H-bond Donors 37.0

H-bond Acceptors 39.0

Rotatable Bonds 82.0

Heavy Atoms 174.0

Ring Count 3.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0065947 VERIFIED: NO

Provenance & Taxonomy

OrganismConus californicus [Animal]

FamilyConotoxin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0206789 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 0.0%, T 62.5%, C 37.5% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic