Peptide Database

Peptide NameGlycoprotein hormones alpha chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC463H721N125O137S14

DescriptionStandard

        FPDGEFTMQGCPECKLKENKYFSKLGAPVYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNAKVENHTECHCSTCYYHKS
    

Molecular Weight10679.34 Da

Isoelectric Point (pI)8.83

Net Charge (pH 7.0)5.92

Net Charge (pH 7.4) 5.39

Charge Density (pH 7.0) 0.0617

GRAVY Index-0.40

Hydrophobic Moment 0.62

Boman Index-0.04

Instability Index52.85

Aliphatic Index 39.69

Aromaticity 0.1042

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 8075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4195.38

LogP -46.54

H-bond Donors 154.0

H-bond Acceptors 160.0

Rotatable Bonds 347.0

Heavy Atoms 739.0

Ring Count 19.0

Amide Bonds 101.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0407521 VERIFIED: YES

Provenance & Taxonomy

OrganismPanthera tigris altaica [Animal]

FamilyGlycoprotein hormones

Tax ID74533

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide11-35; 14-64; 32-86; 36-88; 63-91

Other Mods56:N-linked (GlcNAc...) asparagine; 82:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min