Peptide Database

Peptide Namecycloviolacin O16

Function Ontology

Antiparasitic ▸ Anthelminthic

Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC128H200N32O39S5

DescriptionStandard

        GLPGETCFTGKCYTPGCSCSYPICKKIN
    

Molecular Weight2971.47 Da

Isoelectric Point (pI)8.39

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.42

Charge Density (pH 7.0) 0.0610

GRAVY Index-0.12

Hydrophobic Moment 0.39

Boman Index0.10

Instability Index17.75

Aliphatic Index 41.79

Aromaticity 0.1071

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1122.71

LogP -13.29

H-bond Donors 43.0

H-bond Acceptors 46.0

Rotatable Bonds 91.0

Heavy Atoms 204.0

Ring Count 6.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0019599 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Nematocidal Anthelmintic

TargetTrichostrongylus colubriformis

Activity0.45

MethodIC50

RECORD: Rec_0383910 VERIFIED: YES