Peptide Database

Peptide NameCruzioseptin-3 (CZS-3)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC134H223N41O37

DescriptionStandard

        KRGFLDVVKHIGKAALGAVTHLINQGEQ
    

Molecular Weight3000.46 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)1.94

Net Charge (pH 7.4) 1.62

Charge Density (pH 7.0) 0.0691

GRAVY Index-0.04

Hydrophobic Moment 0.75

Boman Index0.08

Instability Index25.31

Aliphatic Index 111.43

Aromaticity 0.0357

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1270.44

LogP -11.78

H-bond Donors 43.0

H-bond Acceptors 41.0

Rotatable Bonds 104.0

Heavy Atoms 212.0

Ring Count 3.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049080 VERIFIED: YES

Provenance & Taxonomy

OrganismCruziohyla calcarifer [Animal]

FamilyFrog skin active peptide (FSAP); Cruzioseptin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0053255 VERIFIED: YES

Provenance & Taxonomy

OrganismCruziohyla calcarifer [Animal]

FamilyFrog skin active peptide (FSAP); Cruzioseptin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0177568 VERIFIED: YES

Provenance & Taxonomy

OrganismCruziohyla calcarifer [Animal]

FamilyFrog skin active peptide (FSAP); Cruzioseptin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetCandida albicans

RECORD: Rec_0238040 VERIFIED: NO

Provenance & Taxonomy

OrganismCruziohyla calcarifer [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial