Peptide Database

Peptide NamePrecursor of Aurein 2.5

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC81H131N19O21

DescriptionStandard

        GLFDIVKKVVGAFGSLG
    

Molecular Weight1707.02 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0447

GRAVY Index1.08

Hydrophobic Moment 0.57

Boman Index0.45

Instability Index-5.00

Aliphatic Index 125.88

Aromaticity 0.1176

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 638.49

LogP -3.98

H-bond Donors 22.0

H-bond Acceptors 22.0

Rotatable Bonds 57.0

Heavy Atoms 121.0

Ring Count 2.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0055845 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria aurea; Litoria raniformis [Animal]

FamilyAurein

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anticancer

PaperRozek T., Wegener K., Bowie J., Olver I. N., Carver J. A., Wallace J. C., Tyler M. J.. The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis. Eur. J. Biochem, 267, 5330-5341. PMID10951191 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/