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MYP_104604
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Basic Information
Ds-Defensin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
52 amino acids
C240H390N88O69S6
Standard
Sequence
VPAESEAAHLRVRRGFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN
Physicochemical Analysis
5804.60 Da
9.69
6.94
6.48
0.1334
-0.61
0.72
-0.22
92.23
56.35
0.0577
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2568.76
-33.98
99.0
85.0
190.0
403.0
8.0
56.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0302511 VERIFIED: YES
Provenance & Taxonomy
Dermacentor silvarum [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperParasit Vectors. 2015 Jan 15;8:25. | https://www.ncbi.nlm.nih.gov/pubmed/25588982 PMID25588982 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25588982/
RECORD: Rec_0309886 VERIFIED: YES
Provenance & Taxonomy
Dermacentor silvarum [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Micrococcus luteus CMCC63202
50 μM
MIC
PaperMolecular characterization of a defensin gene from a hard tick, Dermacentor silvarum.
RECORD: Rec_0318873 VERIFIED: YES
Provenance & Taxonomy
Dermacentor silvarum [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Bacillus pumilus CMCC 63202
1 μM
MIC
PMID25588982 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25588982/
RECORD: Rec_0345041 VERIFIED: YES
Provenance & Taxonomy
Dermacentor silvarum [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S-typhimurium CVCC542
>50 μM
MIC
PaperMolecular characterization of a defensin gene from a hard tick, Dermacentor silvarum.
RECORD: Rec_0356836 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium bovis (carbenicillin-resistant strain)
20 μM
MIC
PMID25588982 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25588982/
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