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MYP_104604
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Basic Information
Ds-Defensin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
52 amino acids
C240H390N88O69S6
Standard
Sequence
VPAESEAAHLRVRRGFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN
Physicochemical Analysis
5804.60 Da
9.69
6.94
6.48
0.1334
-0.61
0.72
-0.22
92.23
56.35
0.0577
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2568.76
-33.98
99.0
85.0
190.0
403.0
8.0
56.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0123556 VERIFIED: YES
Provenance & Taxonomy
Dermacentor silvarum [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Mouse erythrocytes (0% Hemolysis at 10 microM
10 μM
Hemolysis
PMID25588982 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25588982/
RECORD: Rec_0145476 VERIFIED: YES
Provenance & Taxonomy
Dermacentor silvarum [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus CMCC 26003
20 μM
MIC
PMID25588982 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25588982/
RECORD: Rec_0163833 VERIFIED: YES
Provenance & Taxonomy
Dermacentor silvarum [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
B. pumilus CMCC63202
1 μM
MIC
PaperMolecular characterization of a defensin gene from a hard tick, Dermacentor silvarum.
RECORD: Rec_0176490 VERIFIED: YES
Provenance & Taxonomy
Dermacentor silvarum [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Micrococcus luteus CMCC 63202
50 μM
MIC
PMID25588982 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25588982/
RECORD: Rec_0177371 VERIFIED: YES
Provenance & Taxonomy
Dermacentor silvarum [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Salmonella typhimurium CVCC 542
50 μM
MIC
PMID25588982 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25588982/
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