Peptide Database

Peptide NamePeptide 12

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC103H185N35O28S

DescriptionStandard

        KKSINSLHLAMLKKQRLNRD
    

Molecular Weight2393.85 Da

Isoelectric Point (pI)11.17

Net Charge (pH 7.0)4.85

Net Charge (pH 7.4) 4.59

Charge Density (pH 7.0) 0.2424

GRAVY Index-1.00

Hydrophobic Moment 0.38

Boman Index-0.41

Instability Index17.07

Aliphatic Index 102.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1079.81

LogP -10.90

H-bond Donors 38.0

H-bond Acceptors 35.0

Rotatable Bonds 89.0

Heavy Atoms 167.0

Ring Count 1.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0426675 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity128 μM

MethodMBC

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