Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length467 amino acids

Chemical FormulaC2359H3752N612O681S14

DescriptionStandard

        MMLCALALLTLVPVITGDNAGVKVSITQRGLDYAVTNTIKQVLLKMDIPDHFGTIQVLWINFDYSFTGMKIHFDNFKSEQKFVSGTGVSIAVQITNLNVSGYVTLGRNRTFELFVTTLSISATVAVKSDRNGHPILNMNEDNCLPEIGRFKPQIGNRRSINWILRKITSLFNGFVRTHLKNQICNKLQTLLADLNTQLKTLKAKVSEYAEIDYSLRSPVVFDNSIEMGLKGVFYNTQQRVEPPSSPPAFSLASQNTNMFYIAVSAFTINSAFMVLHRTNVFNIRITDDMVPSVSPIRLSTTTFGAFIPQISETHPDLKLELKVETVKEPIIKFEPNHVILQLLSTVTAYDVQSGNTPTQLFVLNLESVASVQVSVEEGDLAFNLTLEKIEGSMNGKPFKVEKTHFLTVIMHNIVFPIIKAHLAKGFQLPGLLGSYIGKVHIVKPQVKVLNDYVLIGTDIEFEENTSS
    

Molecular Weight52031.63 Da

Isoelectric Point (pI)8.25

Net Charge (pH 7.0)2.47

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0053

GRAVY Index0.10

Hydrophobic Moment 0.83

Boman Index0.13

Instability Index32.96

Aliphatic Index 103.64

Aromaticity 0.0857

Extinction Coeff. Reduced 25900.00

Extinction Coeff. Oxidized 26025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0208105 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria