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MYP_104560
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Basic Information
K7I
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
28 amino acids
C161H289N35O29
Standard
Sequence
IKPIIKPIIKPIIKPIIKPIIKPIIKPI
Physicochemical Analysis
3179.23 Da
10.78
6.75
6.54
0.2412
0.88
0.72
0.34
-30.43
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
969.63
4.58
29.0
36.0
104.0
225.0
7.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0046829 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells [Minimum peptide concentration that caused >10% hemolysis (HC10) = >128 microM]
128 μM
Hemolysis
PMID30742437 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30742437/
RECORD: Rec_0117426 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa 21630
64 μM
MIC
PMID30742437 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30742437/
RECORD: Rec_0126639 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0129982 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli K99
2 μM
MIC
PMID30742437 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30742437/
RECORD: Rec_0144880 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli 25922
8 μM
MIC
PMID30742437 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30742437/
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