Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC728H1135N215O206S5

DescriptionStandard

        MAKVQFKPRPTTDFIVVHCAATKASMDIGVREIRQWHVQQGWLDVGYHFVIRRNGTVEDGRPHNVIGSHVKNYNSRSLGICLVGGIDAKGNPENNFTPEQFNSLKLLLIAQQRQYPHATIVGHRDLDSGKACPSFVVSDWLHEVGI
    

Molecular Weight16355.44 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)3.18

Net Charge (pH 7.4) 2.49

Charge Density (pH 7.0) 0.0218

GRAVY Index-0.30

Hydrophobic Moment 0.68

Boman Index0.01

Instability Index33.55

Aliphatic Index 86.03

Aromaticity 0.0822

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6755.59

LogP -67.44

H-bond Donors 234.0

H-bond Acceptors 222.0

Rotatable Bonds 535.0

Heavy Atoms 1154.0

Ring Count 30.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0368750 VERIFIED: NO

Provenance & Taxonomy

OrganismPseudomonas phage PlaquesPlease [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic