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MYP_104405
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Basic Information
VpBD (V.philippinarum beta defensin; big defensin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
74 amino acids
C384H597N123O106S9
Standard
Sequence
LCLDQKPEMEPFRKDAQQALEPSRQRRWLHRRCLSGRGFCRAICSIFEEPVRGNIDCYFGYNCCRRMFSHYRTS
Physicochemical Analysis
8921.19 Da
9.20
5.88
5.45
0.0794
-0.77
0.78
-0.28
81.47
50.14
0.1216
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3759.46
-38.53
142.0
123.0
294.0
622.0
16.0
79.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004232 VERIFIED: YES
Provenance & Taxonomy
Venerupis philippinarum [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
33-63, 40-57, 44-64
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Proteus mirabilis
26.26 μM
MIC
PMID20975988 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20975988/
RECORD: Rec_0009650 VERIFIED: YES
Provenance & Taxonomy
Venerupis philippinarum [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
26.26 μM
MIC
PMID20975988 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20975988/
RECORD: Rec_0011017 VERIFIED: YES
Provenance & Taxonomy
Venerupis philippinarum [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
33-63, 40-57, 44-64
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphyloccocus aureus
1.64-3.28 μM
MIC
PMID20975988 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20975988/
RECORD: Rec_0042279 VERIFIED: YES
Provenance & Taxonomy
Venerupis philippinarum [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
G+ Staphylococcus aureus
1.64-3.28 μM
MIC
PaperMolecular characterization of a novel big defensin from clam Venerupis philippinarum
RECORD: Rec_0071560 VERIFIED: YES
Provenance & Taxonomy
Venerupis philippinarum [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
33-63, 40-57, 44-64
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus sp
PMID20975988 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20975988/
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