Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length289 amino acids

Chemical FormulaC1436H2262N376O398S10

DescriptionStandard

        MALPRCQQRPSAPSFPDHLPLTHLFPLFTVTARIDAKTGIDYSLVAAPRATAQSLDADLKGEFYSLAHRSTVPFSPLPLALPSDHDRMVYFGASSYFFNTAGIAYHEAGALVFEITEDMIPKDVGFSLDTSLFSAFIPQVSSLALPAQSSCTHRLCSVPGISLNPIVEAQAYAILPNSSLAPLFLLSLVTTHLFFISHLSSSACTSPVPQTKAFPPLLPPPQVRTIQSLMNILTSKILLPRLNGENLLGRMWVLEHPTLRLLHPSGASSLIKSSLLRLIWGKSACRRLQ
    

Molecular Weight31482.25 Da

Isoelectric Point (pI)8.87

Net Charge (pH 7.0)4.34

Net Charge (pH 7.4) 3.51

Charge Density (pH 7.0) 0.0150

GRAVY Index0.25

Hydrophobic Moment 0.67

Boman Index0.17

Instability Index54.03

Aliphatic Index 103.36

Aromaticity 0.0830

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20190.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0282809 VERIFIED: NO

Provenance & Taxonomy

OrganismCorvus moneduloides [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria