Peptide Database

Peptide NamePERN1_TOBAC

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length330 amino acids

Chemical FormulaC1565H2501N451O474S16

DescriptionStandard

        CAVIRDRLFNFNSTGGPDPSIDATFLPQLRALCPQNGDASRRVGLDTGSVDGRVSRAADAGDLPAFFDSVDIQKRKFLTKGLNTQDLVALTGAHTIGTAGEFGRSMVKMSNIEVKTGTNGEIRKVCSAINKGFDVIEDAKTQIEAICPGVVSCADILALAARDSVVATRGLTWSVPTGRRMEYYHHSINKMAMFMVILVLAIDVTMVLGQGTRVGFYSSTCPRAESIVQSNNFDTSYFSNLRNGRGVLESDQKLWTDASTQVFVQRFLGIRGLLGLTFGVTVRAHFQSDPTVAPGILRMHFHDCFVLGCDGSILIEGSDAERTAIPNRNL
    

Molecular Weight35731.38 Da

Isoelectric Point (pI)7.73

Net Charge (pH 7.0)1.24

Net Charge (pH 7.4) 0.57

Charge Density (pH 7.0) 0.0038

GRAVY Index0.01

Hydrophobic Moment 0.76

Boman Index0.06

Instability Index39.45

Aliphatic Index 88.33

Aromaticity 0.0727

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17460.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0256802 VERIFIED: YES

Provenance & Taxonomy

OrganismNicotiana tabacum [Plant]

Tax ID4097

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme