Peptide Database

Peptide NameTrypsin inhibitor MCTI-II TI-1b

Function Ontology

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC123H198N38O38S8

DescriptionStandard

        ICPRIWMECKRDSDCMAQCICVDGHCG
    

Molecular Weight3073.64 Da

Isoelectric Point (pI)5.43

Net Charge (pH 7.0)-1.21

Net Charge (pH 7.4) -1.55

Charge Density (pH 7.0) -0.0447

GRAVY Index0.02

Hydrophobic Moment 0.58

Boman Index-0.03

Instability Index63.71

Aliphatic Index 57.78

Aromaticity 0.0370

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1217.94

LogP -12.44

H-bond Donors 48.0

H-bond Acceptors 46.0

Rotatable Bonds 100.0

Heavy Atoms 207.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0163821 VERIFIED: NO

Provenance & Taxonomy

OrganismMomordica charantia [Plant]; Luffa cylindrica [Plant]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-19; 9-21; 15-26

Bio-Activity Profile

Function

Enzyme inhibitory

RECORD: Rec_0250808 VERIFIED: YES