Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length468 amino acids

Chemical FormulaC2246H3581N591O658S17

DescriptionStandard

        MLPAVIVGLMLVSLTCGENPAVQVILTNKGLQYGKHVGAGWIQEKLESVTFPDISGKLRIGILGNVHYTLTGARITKCDFPEPSVEFYQSATGFKTSVSGLSVALTGEWRAHYGPIHSGGTFNMAVFNVAVTSVVKLGNDTNRHLSVSSVHCDAGVGGVNIQFHGGSRYSRRQGGEDNISGDTDICPKVQESIAILEQHLQAMNVSFNVNQVVTLDLPLTGLPVVDASSLNLGLKGEFYSIKAPAEPPFQAKPFTVPEQPGRMLSVGLSEFTLNSASFGYFSAGVLQAVINDSMIPKFSPVHLNTSSMGPYVPQLPKMFPGLLVSLQVYAREVPLFSFLPGAVCLDLKGAVKAFAIQPNGTQTPLFKLNVDSLFSGKVWIADGRLKGSMKLNNLTVTLVSSEVGTVKTDAIQNILLKVSSIAMAKVNQILGKGVSLPRMKQAELVNTVLELDKGFIAVSSDAQVLMSD
    

Molecular Weight49936.13 Da

Isoelectric Point (pI)8.16

Net Charge (pH 7.0)2.27

Net Charge (pH 7.4) 1.43

Charge Density (pH 7.0) 0.0049

GRAVY Index0.19

Hydrophobic Moment 0.61

Boman Index0.18

Instability Index35.21

Aliphatic Index 99.89

Aromaticity 0.0726

Extinction Coeff. Reduced 29910.00

Extinction Coeff. Oxidized 30160.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239036 VERIFIED: NO

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria