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MYP_104210
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Basic Information
Gaegurin 5 (1-11)[V8W]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
11 amino acids
C64H94N14O13
Standard
Sequence
FLGALFKWASK
Physicochemical Analysis
1267.52 Da
10.00
1.76
1.55
0.1598
0.63
0.49
0.35
-25.95
89.09
0.2727
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
442.38
-0.53
16.0
15.0
40.0
91.0
4.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007191 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 16884301 PMID16884301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16884301/
RECORD: Rec_0040467 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
A498
214.33 μg/mL
IC50
PaperPubMed PMID: 16884301 PMID16884301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16884301/
RECORD: Rec_0061113 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
198.87 μg/mL
IC50
PaperPubMed PMID: 16884301 PMID16884301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16884301/
RECORD: Rec_0064501 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphyloccus aureus
12.5 μg/mL
MIC
PMID14739294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14739294/
RECORD: Rec_0075218 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermis
25 μg/mL
MIC
PMID14739294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14739294/
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