Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC315H497N81O89S2

DescriptionStandard

        PDLSGYEKFGLGNVKYNISRIHVTAVEFPSASISLIPGTGIKLVIGNASLTVDMNWNIRTWML
    

Molecular Weight6906.93 Da

Isoelectric Point (pI)8.77

Net Charge (pH 7.0)1.05

Net Charge (pH 7.4) 0.93

Charge Density (pH 7.0) 0.0166

GRAVY Index0.25

Hydrophobic Moment 0.53

Boman Index0.22

Instability Index18.78

Aliphatic Index 108.25

Aromaticity 0.0952

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2705.48

LogP -23.63

H-bond Donors 95.0

H-bond Acceptors 93.0

Rotatable Bonds 224.0

Heavy Atoms 487.0

Ring Count 12.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0155370 VERIFIED: NO

Provenance & Taxonomy

OrganismPiaya cayana [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria