Peptide Database

Peptide NameACT-Human Cathelicidin/LL-37 (16-32)[F2W][I5W][I9W][F12W]-AMD

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC114H168N34O24

DescriptionStandard

        EWKRWVQRWKDWLRNLV
    

Molecular Weight2398.77 Da

Isoelectric Point (pI)10.90

Net Charge (pH 7.0)2.84

Net Charge (pH 7.4) 2.66

Charge Density (pH 7.0) 0.1668

GRAVY Index-1.35

Hydrophobic Moment 0.86

Boman Index-0.37

Instability Index107.99

Aliphatic Index 80.00

Aromaticity 0.2353

Extinction Coeff. Reduced 22000.00

Extinction Coeff. Oxidized 22000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 990.60

LogP -3.02

H-bond Donors 37.0

H-bond Acceptors 27.0

Rotatable Bonds 77.0

Heavy Atoms 172.0

Ring Count 8.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239636 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus FDA 486

Activity5 μM

MethodMIC

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