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MYP_104143
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Basic Information
[Arg]3-VmCT1-NH2 (Derived from VmCT1)
Anticancer
Anticancer ▸ Antitumor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C76H115N19O16
Standard
Sequence
FLRALWNVAKSVF
Physicochemical Analysis
1550.84 Da
11.00
1.76
1.55
0.1353
0.89
0.71
0.29
51.75
120.00
0.2308
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
579.55
-1.87
21.0
18.0
48.0
111.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031294 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida tropicalis IOC 4560
0.8 μM
MIC
PaperRepurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0048545 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus subtilis ATCC 6633
0.8 μM
MIC
PaperRepurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0085769 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Antitumor Antiparasitic Antiprotozoal
NH2): Escherichia coli SBS 363, Serratia marcescens ATCC 4112, Enterobacter cloacae -12, Pseudomonas aeruginosa ATCC 27853, Micrococcus luteus A270, Staphylococcus aureus ATCC 29213, Bacillus megaterium ATCC 10778, Bacillus subtilis ATCC 6633, Candida albicans MDM8, Candida tropicalis IOC 4560
PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0117725 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Antitumor Antiparasitic Antiprotozoal
Plasmodium gallinaceum
0.57±0.02
IC50
PMID33442883;31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33442883/
RECORD: Rec_0128142 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Antitumor Antiparasitic Antiprotozoal
MCF-7
20.6±3.1
IC50
PMID33442883;31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33442883/
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