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MYP_104124
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Basic Information
TPk
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
13 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
VRRFXWWWXFLRR
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0075678 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 5,9
Bio-Activity Profile
Cytotoxic
Mouse fibroblasts NIH 3T3
48 μM
IC50
PMID17059217 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17059217/
RECORD: Rec_0096787 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Nlys
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0135081 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 5,9
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa KCTC 1637
8 μM
MIC
PMID17059217 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17059217/
RECORD: Rec_0144705 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 5,9
Bio-Activity Profile
Antimicrobial Antibacterial
Human cervical carcinoma HeLa
100 μM
IC50
PMID17059217 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17059217/
RECORD: Rec_0158498 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 5,9
Bio-Activity Profile
Cytotoxic
Mouse fibroblasts NIH 3T3
52 μM
IC50
PMID17059217 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17059217/
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