Peptide Database

Peptide NameΔ8-22

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Complement inhibitor

Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor Of Complement Pathway

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC71H123N19O21S2

DescriptionStandard

        PAICQRAEIEACILL
    

Molecular Weight1642.98 Da

Isoelectric Point (pI)4.53

Net Charge (pH 7.0)-1.06

Net Charge (pH 7.4) -1.15

Charge Density (pH 7.0) -0.0704

GRAVY Index0.99

Hydrophobic Moment 0.18

Boman Index0.26

Instability Index101.41

Aliphatic Index 150.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 636.32

LogP -3.98

H-bond Donors 24.0

H-bond Acceptors 22.0

Rotatable Bonds 54.0

Heavy Atoms 113.0

Ring Count 1.0

Amide Bonds 15.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0156769 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Complement inhibitor

TargetSheep erythrocytes

Activity770 μM

MethodHemolysis

RECORD: Rec_0316948 VERIFIED: YES